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  • Amiodarone is the most appropriate antiarrhythmic agent because it has higher effectiveness in this setting and a very low propensity for provoking a prorhythmic effect. Although adverse effects may occur, they are usually dose related and less likely to occur at a dose of 200 mg/day.
  • Flecainide is contraindicated because of the high risk of prorhythmias with class 1C agents in the setting of impaired LV function and ischemic heart disease.
  • Sotalol should be avoided because of the severe LV dysfunction and risk of prorhythmic effects.
  • Quinidine and procainamide both have negative inotropic effects and should also be avoided because of potential prorhythmic effects.
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